Module Details

Module Code: BIOT7003
Title: Industrial Biotechnology
Long Title: Industrial Biotechnology
NFQ Level: Intermediate
Valid From: Semester 1 - 2022/23 ( September 2022 )
Duration: 1 Semester
Credits: 5
Field of Study: 4218 - Biotechnology
Module Delivered in: 1 programme(s)
Module Description: This module is designed to familiarise students with processes,layout and operation of biotechnology processes including traditional microbial and modern biopharmaceutical production processes.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Outline the principles of microbial fermentations and discuss selected industrial microbial processes.
LO2 Describe the requirements and operation of an upstream process for the production of a biopharmaceutical.
LO3 Discuss a typical downstream process for a biopharmaceutical.
LO4 Identify the main considerations for ensuring the production of a pure, sterile and endotoxin free biopharmaceutical.
LO5 Provide an overview of the regulatory processes inherent in commercial biopharmaceutical production.
LO6 Demonstrate practical competence in selected biotechnology related techniques.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
12841 BIOT6001 Introduction to Biotechnology
12930 BIOM6006 Microbial Diversity
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
None
 
Indicative Content
Microbial fermentations
An overview of microbial fermentations. Description of primary and secondary metabolites and bioconversions. A description of selected economically important microbial fermentations
Upstream
Requirements and steps involved in the upstream process for a biopharmaceutical: Cell banks, media requirements, bioreactor design, operating system.
Downstream
A general summary of the main requirements and stages in downstream processing: filtration, chromatography, virus removal, endotoxin detection, clean rooms and formulation.
Regulatory processes
An overview of the role of the FDA in ensuring the safe production of biotechnology related products. This section will also provide an overview of the clinical trial process.
Practical sessions
Laboratory sessions on selected areas of a biotechnology based production process. Including if possible Bioreactor operation, aseptic process, protein purification, environmental monitoring, endotoxin testing and site visits.
Module Content & Assessment
Assessment Breakdown%
Coursework100.00%

Assessments

Coursework
Assessment Type Other % of Total Mark 30
Timing Week 7 Learning Outcomes 1,2
Assessment Description
Theory based assessment of lecture material with multiple choice and short answer questions
Assessment Type Other % of Total Mark 40
Timing Week 13 Learning Outcomes 3,4,5
Assessment Description
Theory based assessment of lecture material with multiple choice and short answer questions and a case study
Assessment Type Written Report % of Total Mark 30
Timing Every Second Week Learning Outcomes 1,2,3,4,6
Assessment Description
Written reports and analysis of biotechnology based laboratory practical sessions .
No End of Module Formal Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Class based instruction Every Week 2.00 2
Lab Contact Practical laboratory Instruction Every Week 2.00 2
Independent & Directed Learning (Non-contact) Non Contact Independent & directed learning Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
This module has no Part Time workload.
 
Module Resources
Recommended Book Resources
  • Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm. (2019), Pharmaceutical Biotechnology: Fundamentals and Applications, 1st. [ISBN: 978-303000709].
  • Christoph Wittmann, James C. Liao. (2017), Industrial Biotechnology: Products and Processes, American Society for Microbiology (ASM), [ISBN: 9783527341818].
  • Bernard R. Glick, Cheryl L. Patten. (2022), Molecular Biotechnology: Principles and Applications of Recombinant DNA, 6th. [ISBN: 978-168367364].
Supplementary Book Resources
  • Jayanta Kumar Patra, Chethala N. Vishnuprasad, Gitishree Das. (2018), Microbial Biotechnology: Applications in Agriculture and Environment, 1st. [ISBN: 978-981106846].
  • Colin Ratledge and Bjorn Kristiansen. (2006), Basic Biotechnology, 3rd. Cambridge University Press;, [ISBN: 9780521549585].
This module does not have any article/paper resources
This module does not have any other resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_SBIBI_7 Bachelor of Science in Applied Biosciences and Biotechnology 5 Mandatory