Module Details
Module Code: |
CHEO7003 |
Title: |
Topics in Organic Chemistry
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Long Title:
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Topics in Organic Chemistry
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NFQ Level: |
Intermediate |
Valid From: |
Semester 1 - 2023/24 ( September 2023 ) |
Field of Study: |
4423 - Organic Chemistry
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Module Description: |
This module further develops concepts such as reaction mechanisms, syntheses and processes in the production of organic chemicals, which were introduced at level 6 or equivalent
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Learning Outcomes |
On successful completion of this module the learner will be able to: |
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Learning Outcome Description |
LO1 |
Write reaction sequences for the synthesis of complex organic molecules |
LO2 |
Outline strategies in organic synthesis and retrosynthesis |
LO3 |
Evaluate proton nuclear magnetic resonance and it's role in molecular determination |
LO4 |
Explain the reactions of selected heterocyclic compounds |
Dependencies |
Module Recommendations
This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
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Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
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No incompatible modules listed |
Co-requisite Modules
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No Co-requisite modules listed |
Requirements
This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
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Students will have completed the level 6 modules, Organic Chemistry Fundamentals and Organic Chemistry or have completed equivalent level organic chemistry modules |
Indicative Content |
Carbonyl Chemistry
Carbanions; regioselectivity of enolisation reactions; thermodynamic versus kinetic enolates; reactions of active methylene compounds; 1,2 versus 1,4 addition to conjugated systems; aldol, Claisen and Dieckman condensations; the haloform and Michael addition; Robinson annulation
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Stereochemistry
Chirality; stereocentres, enantiomers, diastereomers, meso compounds; resolution of racemic mixtures
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Amino acids, Peptides and Proteins
Synthesis of proteins, protection and activation of functional groups and peptide bond formation; solid-phase peptide synthesis; primary, secondary, tertiary and quaternary structures of proteins
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Nuclear Magnetic Resonance Spectroscopy
Origins of proton NMR, absorbances, chemical shift, integration ratios, spin-spin coupling, diastereotopic and enanatiotopic protons, structure determination
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Heterocyclic Compounds
Nomenclature of frequently-encountered heterocycles; reactions, regioselectivity of electrophilic and nucleophilic substitution reactions
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Synthesis Design
Strategies in organic synthesis and retrosynthesis, protecting groups.
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Module Content & Assessment
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Assessment Breakdown | % |
Coursework | 100.00% |
Assessments
No End of Module Formal Examination |
Reassessment Requirement |
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.
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The University reserves the right to alter the nature and timings of assessment
Module Workload
Workload: Full Time |
Workload Type |
Contact Type |
Workload Description |
Frequency |
Average Weekly Learner Workload |
Hours |
Lecture |
Contact |
Organic chemistry theory |
Every Week |
4.00 |
4 |
Independent & Directed Learning (Non-contact) |
Non Contact |
Personal study |
Every Week |
3.00 |
3 |
Total Hours |
7.00 |
Total Weekly Learner Workload |
7.00 |
Total Weekly Contact Hours |
4.00 |
Workload: Part Time |
Workload Type |
Contact Type |
Workload Description |
Frequency |
Average Weekly Learner Workload |
Hours |
Lecture |
Contact |
Organic Chemistry Theory |
Every Week |
4.00 |
4 |
Independent & Directed Learning (Non-contact) |
Non Contact |
Personal Study |
Every Week |
3.00 |
3 |
Total Hours |
7.00 |
Total Weekly Learner Workload |
7.00 |
Total Weekly Contact Hours |
4.00 |
Module Resources
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Recommended Book Resources |
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McMurray John E.. (2016), Organic Chemistry, 9th. Brooks Cole, [ISBN: 9781305080485].
| Supplementary Book Resources |
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Sykes P.. (1986), A Guidebook to Mechanisms in Organic Chemistry, 6th. Prentice Hall, [ISBN: 13:9780130832191].
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Michael B. Smith, Jerry March. (2007), March's advanced orgainic chemistry, 6th. Wiley, [ISBN: 978-0-471-72091-1].
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Ege S.. (2004), Organic Chemistry, Structure and Reactivity, 5th. Houghton Mifflin, [ISBN: 0618318097].
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Morrison R. T., Boyd R. N.. (2005), Organic Chemistry, 7th. Prentice Hall, [ISBN: 0132678160].
| This module does not have any article/paper resources |
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This module does not have any other resources |
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