Module Details

Module Code: CHEO6006
Title: Pharmaceutical Chemistry
Long Title: Pharmaceutical Chemistry
NFQ Level: Fundamental
Valid From: Semester 1 - 2019/20 ( September 2019 )
Duration: 1 Semester
Credits: 5
Field of Study: 4423 - Organic Chemistry
Module Delivered in: 3 programme(s)
Module Description: This module introduces the learner to pharmaceutical agents. It applies fundamental chemical principles to pharmaceutical molecules and it highlights the link between pharmaceuticals and organic chemistry.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Outline the mode of action of a range of pharmaceutical agents
LO2 Discuss the chemistry of nitrogen, selected natural products and pharmaceutical molecules
LO3 Apply fundamental chemistry to explain the physicochemical properties of pharmaceutical molecules
LO4 Describe the role of quality control in the manufacture of pharmaceuticals
LO5 Prepare and analyse pharmaceutical compounds and present a written report of work completed
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
Students will have completed the following level 6 modules: Chemical Principles, General Physical & Inorganic Chemistry, Organic Chemistry Fundamentals or other equivalent level chemistry modules
 
Indicative Content
Introduction to Pharmaceuticals
Classification and description of different groups of medicines and their mode of action
Nitrogen and Natural Product Chemistry
Amines and nitrogen-containing pharmaceutical molecules - reactions and synthesis; racemates; resolution of racemates; chemistry of amino acids, proteins, carbohydrates
Physicochemical Properties of Pharmaceutical Molecules
pKa values; ionization; drug-target interactions; solubility, salt formation, absorption; metabolism
Introduction to Quality Control of Pharmaceuticals
Active product ingredients (API); manufacture, formulation, sources of impurities, GMP, GLP
Practical Programme
Selected practicals in synthesis, extraction and analysis of pharmaceutical and natural product molecules
Module Content & Assessment
Assessment Breakdown%
Coursework50.00%
End of Module Formal Examination50.00%

Assessments

Coursework
Assessment Type Short Answer Questions % of Total Mark 20
Timing Week 6 Learning Outcomes 1,2,3
Assessment Description
In-class theory assessment
Assessment Type Practical/Skills Evaluation % of Total Mark 30
Timing Every Week Learning Outcomes 3,5
Assessment Description
Performance, reports and calculations assignments.
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 50
Timing End-of-Semester Learning Outcomes 1,2,3,4,5
Assessment Description
End-of-Semester Final Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Delivery of theory Every Week 3.00 3
Lab Contact Synthesis and analysis of pharmaceutical and natural product molecules Every Week 2.00 2
Independent & Directed Learning (Non-contact) Non Contact Personal study Every Week 2.00 2
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 5.00
Workload: Part Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Delivery of Theory Every Week 3.00 3
Lab Contact Synthesis and analysis of Pharmaceutical and natural product molecules Every Week 2.00 2
Independent & Directed Learning (Non-contact) Non Contact Personal study Every Week 2.00 2
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 5.00
 
Module Resources
Recommended Book Resources
  • McMurray John E.. (2016), Organic Chemistry, 9th. Brooks Cole, [ISBN: 9781305080485].
  • Graham L. Patrick. (2017), An Introduction to Medicinal Chemistry, 6th. Oxford University Press, [ISBN: 9780198749691].
Supplementary Book Resources
  • Moynihan Humphrey, Crean Abina. (2009), Physicochemical Basis of Pharmaceuticals, Oxford University Press, [ISBN: 9780199232840].
  • Bettelheim Frederick A., Brown William H., Campbell Mary K., Farrell Shawn O., Torres Omar. (2016), Introduction to General, Organic And Biochemistry, 11th. Brooke's Cole, [ISBN: 9781285869759].
This module does not have any article/paper resources
This module does not have any other resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_SCHQA_8 Bachelor of Science (Honours) in Analytical Chemistry with Quality Assurance 4 Mandatory
CR_SCHEM_7 Bachelor of Science in Analytical and Pharmaceutical Chemistry 4 Mandatory
CR_SCHEM_6 Higher Certificate in Science in Chemistry 4 Mandatory