Module Details

Module Code: CHEA8004
Title: Instrumental Methods
Long Title: Instrumental Methods
NFQ Level: Advanced
Valid From: Semester 1 - 2019/20 ( September 2019 )
Duration: 1 Semester
Credits: 5
Field of Study: 4424 - Analytical Chemistry
Module Delivered in: 1 programme(s)
Module Description: This module further develops the theory and practice of selected instrumental analysis techniques such as electroanalytical, thermal and particle size analysis. It also provides practical experience with derivatisation and internal standardization methods used in instrumental analysis.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Critically assess the principles of operation of potentiometric and amperometric methods of analysis and the development of the corresponding sensor devices.
LO2 Interpret the principles of the most commonly used thermal analysis methods and evaluate their application in pharmaceutical analysis.
LO3 Apprise the role of particle sizing in the chemical/pharmaceutical industry and critically compare various sizing methods.
LO4 Critically comprehend lab experimental methods related to instrumental analysis.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
No requirements listed
 
Indicative Content
Electroanalytcial methods
Review of electrochemical principles. Electroanalytical methods: operation principles of potentiometric and amperometric techniques, quantifications using ion-selective electrodes (ISE).
Thermal Analysis
Thermogravimetry(TG),Differential Thermal Analysis(DTA), Differential Scanning Calorimetry(DSC)-principles,instrumentation,practice and application in anlysis of pharmaceutical products.
Particle size analysis
Particle sizing principles and modalities; sample preparation; spectroscopy and imaging methods for particle size analysis. Application of particle sizing in the pharmaceutical technology. Time, cost, on-line analysis, limitations.
Laboratory Practices
Selectivity of potentiometric analysis, pH effect on ISE analysis, differential scanning calorimetry for drugs analysis, automated electrochemcial titrations, particle size analysis of powdered samples, scanning electron microscopy of powdered samples, etc.
Module Content & Assessment
Assessment Breakdown%
Coursework100.00%

Assessments

Coursework
Assessment Type Short Answer Questions % of Total Mark 30
Timing Week 7 Learning Outcomes 1,3
Assessment Description
Theory test. Topics may include: ion-selective electrodes, pH electrodes, potentiometric titration, amperometry, dynamic light scattering, etc
Assessment Type Short Answer Questions % of Total Mark 20
Timing Week 10 Learning Outcomes 2,3
Assessment Description
Theory test. Topics may include: instrumentation for thermal analysis, calibrations and quantitative determinations, laser scattering and microscopy
Assessment Type Presentation % of Total Mark 20
Timing Week 12 Learning Outcomes 3
Assessment Description
Presentation on particle size analysis and their application in pharmaceuticals manufacturing.
Assessment Type Practical/Skills Evaluation % of Total Mark 30
Timing Every Week Learning Outcomes 4
Assessment Description
Demonstrate proficiency in lab practicals related to electrochemical, thermal and particle size analysis.
No End of Module Formal Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Potentiometric, Amperometric, Thremal and Particle Size Methods Every Week 2.00 2
Lab Contact Lab practicals on electrochemcial, thermal and particle size analysis Every Week 2.00 2
Independent & Directed Learning (Non-contact) Non Contact Personal study Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
Workload: Part Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Potentiometric, Amperometric, Thremal and Particle Size Methods Every Week 2.00 2
Lab Contact Lab practicals on electrochemcial, thermal and particle size analysis Every Week 2.00 2
Independent & Directed Learning (Non-contact) Non Contact Personal study Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • Simon Gaisford. (2015), Principles of Thermal Analysis and Calorimetry, 2nd. Royal Society of Chemistry, p.25, [ISBN: 9781782620518].
Supplementary Book Resources
  • Anette Muellertz, Yvonne Perrie, Thomas Rades. (2016), Analytical Techniques in the Pharmaceutical Sciences,, 1st. Spirnger, [ISBN: 9781493940271].
Recommended Article/Paper Resources
Other Resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_SCHQA_8 Bachelor of Science (Honours) in Analytical Chemistry with Quality Assurance 7 Mandatory