Module Details

Module Code: CHEA7004
Title: Analytical Practice & Protocol
Long Title: Analytical Practice & Protocol
NFQ Level: Intermediate
Valid From: Semester 1 - 2019/20 ( September 2019 )
Duration: 1 Semester
Credits: 5
Field of Study: 4424 - Analytical Chemistry
Module Delivered in: 3 programme(s)
Module Description: This module further develops the theory and practice of analytical chemistry, with specific reference to the areas of spectroscopic and chromatographic instruments, protocols and applications.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Solve quantitative analytical problems based on analytical data using established calibration techniques.
LO2 Explain techniques used for sampling, sample pre-treatment and data analysis as part of the total analytical process.
LO3 Discuss (compare and contrast) operation principles and instrumentation of selected spectroscopic and chromatographic methods associated with modern instrumental analysis.
LO4 Appraise the application of spectroscopic and chromatographic analytical practices in pharmaceutical and biopharmaceutical manufacturing.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
No requirements listed
 
Indicative Content
Total analytical process
Sampling, sample pre-treatment and separation techniques. Standard addition and internal standard methods of quantitation. Types of error in analysis. Statistical evaluation of analytical data. Analytical calculations based on spectroscopic or chromatographic data.
Spectroscopy
Holistic evaluation of atomic and molecular abrsorption and emsssion spectroscopy instrumentation: sources of radiation, optical system and detection. Detailed description of thermal and ICP atomic absorption, X-ray and optical fluorescence spectroscopies.
Chromatography
Assessment and optimisation of parameters for LC and GC. LC normal and reverse approaches. Gas chromatography with non-mass dependant and MS detectors (CI and EI). LC hyphenated with magnetic sector-MS. Electrophoresis. Preparative Chromatography.
Analytical practices in pharmaceutical manufacturing
Compare and contrast spectroscopic and chromatographic methods. Best practices, interference and chemical derivatisations used in pharmaceutical analysis. Time, cost, applicability to on-line quality control, limitations.
Module Content & Assessment
Assessment Breakdown%
Coursework40.00%
End of Module Formal Examination60.00%

Assessments

Coursework
Assessment Type Short Answer Questions % of Total Mark 15
Timing Week 5 Learning Outcomes 1,2
Assessment Description
Theory test including topics such as sampling, pre-treatments, calibration, data analysis.
Assessment Type Short Answer Questions % of Total Mark 15
Timing Week 9 Learning Outcomes 3
Assessment Description
Theory test including topics such as sources of radiation, optical systems, chromatrography columns and detectors (compare and contrast).
Assessment Type Presentation % of Total Mark 10
Timing Week 10 Learning Outcomes 4
Assessment Description
Presentation on application of spectroscopy and chromatography methods in pharmaceutical and biopharmaceutical analysis
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 60
Timing End-of-Semester Learning Outcomes 1,2,3,4
Assessment Description
End-of-Semester Final Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Module Content delivery Every Week 4.00 4
Independent & Directed Learning (Non-contact) Non Contact Student undertakes independent study Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
Workload: Part Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Module Content delivery Every Week 4.00 4
Independent & Directed Learning (Non-contact) Non Contact Student undertakes independent study Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • Douglas A. Skoog... [et al.]. (2013), Fundamentals of Analytical Chemistry, 9th. Chapters: 6,7,8,27,28, Cengage Learning, Inc, CA, United States, [ISBN: 9780495558286].
Supplementary Book Resources
  • Anette Muellertz, Yvonne Perrie, Thomas Rades. (2016), Analytical Techniques in the Pharmaceutical Sciences, 1st. Spirnger, [ISBN: 9781493940271].
  • Elsa Lundanes, Leon Reubsaet, Tyge Greibrokk. (2013), Basic Principles, Sample Preparations and Related Methods, 1. John Wiley & Sons Ltd., United Kingdom, [ISBN: 3527336206].
Recommended Article/Paper Resources
  • Institute of Validation Technology. Step-by-Step Analytical Methods Validation and Protocol in the Quality System Compliance Industry.
Supplementary Article/Paper Resources
This module does not have any other resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_SCHQA_8 Bachelor of Science (Honours) in Analytical Chemistry with Quality Assurance 5 Mandatory
CR_SESST_8 Bachelor of Science (Honours) in Environmental Science and Sustainable Technology 5 Mandatory
CR_SCHEM_7 Bachelor of Science in Analytical and Pharmaceutical Chemistry 5 Mandatory