Module Details

Module Code: BIOE8005
Title: Biomed Fluid & Mass Transport
Long Title: Biomed Fluid & Mass Transport
NFQ Level: Advanced
Valid From: Semester 1 - 2016/17 ( September 2016 )
Duration: 1 Semester
Credits: 5
Field of Study: 5212 - Biomedical Engineering
Module Delivered in: 1 programme(s)
Module Description: This module will introduce the students to the rheological properties and transport of non-Newtonian/viscoelastic fluids which are ubiquitous in biological systems. The course then leads on to the processes that control the transport of species across natural and synthetic barriers and the kinetics of associated reactions.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Derive equations for flow of Newtonian and non-Newtonian fluid in tubes and and employ these equations in the solution of flow problems.
LO2 Explain and analyse the mechanics of blood flow
LO3 Interpret rheological data for viscoselastic biological materials.
LO4 Discuss the principles of mass transfer and the factors affecting rates of mass transfer
LO5 Employ principles of mass transfer in biomedical applications including blood oxygenation, dialysis and drug delivery systems.
LO6 Characterise biochemical reaction kinetics.
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
No requirements listed
 
Indicative Content
Shear Flow of Newtonian and non-Newtonain Fluids
Shear and time dependent nature of non-Newtonian fluid. Derivation of equations for pipe flow of Newtonian, Bingham, Casson and power law fluids. Application of viscometric data to solve pipe flow problems for these fluids. Introduction to time-dependent/thixotropic fluids and flow of suspensions.
Viscoelastic Fluids
Viscoelastic properties of biological fluids, oscillatory shear, linear viscoelasticity and relationships between functions of linear viscoelasticity, Kelvin and Maxwell models, measurement of viscoelastic properties and interpretation of data
Mechanics of Blood Flow
Pressure in the heart, energy in branching systems. Laminar flow and the viscosity of blood. Use of equations of motion and continuity in blood flow problems, velocity flow profiles in tube flow, flow of blood in capillaries, effect of haemocrit on blood flow properties, Fahraeus-Lindquist effect. Sources and effects of turbulent flow on blood.
Mass Transfer
Modes of mass transfer: diffusion, convection, transport of mass against diffusion gradients. Mass balances, molecular diffusion, mass and gas diffusivities, Fick’s law.
Diffusion Through Membranes and Films
Non-porous membranes, partition coefficients, porous membranes, ultrafiltration membranes, hollow fibre membranes, kidney dialysers, blood oxygenation equipment, osmotic pressure and molecular weight. Lung function - Hill Equation.
Mass Transfer Phenomena in Biological Systems
Drug delivery – tablet, injectable, patches. Analysis of drug diffusion - application of mass transfer priciples. Cultivation of mammalian cells in suspension. Biological catalysis: Enzymatic reactions, enzyme-substrate kinetics, Michaelis-Menten equation/constants.
Module Content & Assessment
Assessment Breakdown%
Coursework30.00%
End of Module Formal Examination70.00%

Assessments

Coursework
Assessment Type Short Answer Questions % of Total Mark 15
Timing Week 4 Learning Outcomes 1,2
Assessment Description
In class exam
Assessment Type Short Answer Questions % of Total Mark 15
Timing Week 10 Learning Outcomes 4,5
Assessment Description
In class exam
End of Module Formal Examination
Assessment Type Formal Exam % of Total Mark 70
Timing End-of-Semester Learning Outcomes 1,2,3,5,6
Assessment Description
End-of-Semester Final Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact In class lectures Every Week 4.00 4
Independent & Directed Learning (Non-contact) Non Contact Student directed learning Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
Workload: Part Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact In class lectures Every Week 4.00 4
Independent & Directed Learning (Non-contact) Non Contact Student Directed Learning Every Week 3.00 3
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 4.00
 
Module Resources
Recommended Book Resources
  • Arthur B. Ritter, Stanley Reisman, Bozena B. Michniak. (2005), Biomedical Engineering Principles, 1. Taylor and Francis, p.312, [ISBN: 9780824796167].
  • Kleinstreuer, C.. (2006), Biofluid Dynamics, 1. CRC Press, p.493, [ISBN: 978-0-8493-2221-1].
  • by George A. Truskey, Fan Yuan, David F. Katz.. (2010), Transport phenomena in biological systems, 2nd Edition. Pearson, [ISBN: 9780135131541].
Supplementary Book Resources
  • Fung, Y.C.. (1997), Biomechanics - Circulation, 2. Springer, p.571, [ISBN: 0-387-94384-6].
  • Ronald L. Fournier. (1998), Basic Transport Phenomena in Biomedical Engineering, Taylor and Francis, [ISBN: 9781560327080].
This module does not have any article/paper resources
This module does not have any other resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_EBIOM_8 Bachelor of Engineering (Honours) in Biomedical Engineering 8 Mandatory