Module Details

Module Code: CHEO7004
Title: BioPharmaChem Applications
Long Title: BioPharmaChem Applications
NFQ Level: Intermediate
Valid From: Semester 1 - 2019/20 ( September 2019 )
Duration: 1 Semester
Credits: 5
Field of Study: 4423 - Organic Chemistry
Module Delivered in: 2 programme(s)
Module Description: This module presents topics in the history, development, production, applications, and biotechnology of pharmaceuticals.
 
Learning Outcomes
On successful completion of this module the learner will be able to:
# Learning Outcome Description
LO1 Summarise the development of the modern pharmaceutical / biopharmaceutical industry and discuss the emergence of the associated regulations
LO2 Describe the main activities involved in developing new drug products using traditional and modern methods
LO3 Discuss the chemistry and action of selected pharmaceutical agents including their design and production
LO4 Evaluate the use of biotechnological methods for the production of biopharmaceuticals
LO5 Assess the key quality requirements for biopharmaceutical products
Dependencies
Module Recommendations

This is prior learning (or a practical skill) that is strongly recommended before enrolment in this module. You may enrol in this module if you have not acquired the recommended learning but you will have considerable difficulty in passing (i.e. achieving the learning outcomes of) the module. While the prior learning is expressed as named MTU module(s) it also allows for learning (in another module or modules) which is equivalent to the learning specified in the named module(s).
Incompatible Modules
These are modules which have learning outcomes that are too similar to the learning outcomes of this module. You may not earn additional credit for the same learning and therefore you may not enrol in this module if you have successfully completed any modules in the incompatible list.
No incompatible modules listed
Co-requisite Modules
No Co-requisite modules listed
Requirements

This is prior learning (or a practical skill) that is mandatory before enrolment in this module is allowed. You may not enrol on this module if you have not acquired the learning specified in this section.
No requirements listed
 
Indicative Content
Pharmaceutical and Biopharmaceutical Industries
History and development of the global industries; the contribution of the industry to the Irish economy
Discovery and Development of Small Molecule Pharmaceuticals
Traditional and modern approaches; lead molecules and lead optimization studies, combinatorial methods, chemical process development; regulatory affairs
Chemistry of Small Molecule Pharmaceuticals
Development, synthesis, pharmacological action, structure-activity relationships and chemistry of selected pharmaceutical agents
Biotechnological Processes
Upstream and downstream processes - recombinant DNA, monoclonal antibody technology, cell culture systems, industrial fermentation, harvesting and purification methods, scale up issues
Quality Assurance for Biopharmaceuticals
Cleaning, sterilization and contamination control; sampling and testing activities; product stability; ICH guidelines
Module Content & Assessment
Assessment Breakdown%
Coursework100.00%

Assessments

Coursework
Assessment Type Presentation % of Total Mark 20
Timing Week 3 Learning Outcomes 1
Assessment Description
Design, production and presentation of an e-poster on assigned pharmaceutical topic
Assessment Type Short Answer Questions % of Total Mark 20
Timing Week 4 Learning Outcomes 1,4
Assessment Description
Theory test - biotechnology of pharmaceuticals
Assessment Type Short Answer Questions % of Total Mark 30
Timing Week 8 Learning Outcomes 2,3
Assessment Description
Theory test - pharmaceuticals
Assessment Type Short Answer Questions % of Total Mark 30
Timing Week 8 Learning Outcomes 4,5
Assessment Description
Theory test - biotechnology
No End of Module Formal Examination
Reassessment Requirement
Repeat examination
Reassessment of this module will consist of a repeat examination. It is possible that there will also be a requirement to be reassessed in a coursework element.

The University reserves the right to alter the nature and timings of assessment

 

Module Workload

Workload: Full Time
Workload Type Contact Type Workload Description Frequency Average Weekly Learner Workload Hours
Lecture Contact Pharmaceutical Applications Every Week 3.00 3
Independent & Directed Learning (Non-contact) Non Contact Personal study Every Week 4.00 4
Total Hours 7.00
Total Weekly Learner Workload 7.00
Total Weekly Contact Hours 3.00
This module has no Part Time workload.
 
Module Resources
Recommended Book Resources
  • Graham L. Patrick. (2017), An Introduction to Medicinal Chemistry, 6th. Oxford University Press, [ISBN: 9780191073915].
  • Gary Walsh. (2007), Pharmaceutical Biotechnology, Wiley & Sons, [ISBN: 9780470012444].
  • Gary Walsh. (2003), Biopharmaceuticals: Biochemistry and Biotechnology, J. Wiley, New York, [ISBN: 978-0-470-84327-7].
Supplementary Book Resources
  • H. P. Rang. (2006), Drug Discovery and Development, Churchill Livingstone, Elsevier, [ISBN: 0443064202].
  • Ege S.. (2004), Organic Chemistry, Structure and Reactivity, 5th. Houghton Mifflin, [ISBN: 0618318097].
  • Thomas G.. (2007), Medicinal Chemistry: An Introduction, Wiley & Sons Ltd, US, [ISBN: 978-0-470-02598-7].
This module does not have any article/paper resources
Other Resources
 
Module Delivered in
Programme Code Programme Semester Delivery
CR_SCHQA_8 Bachelor of Science (Honours) in Analytical Chemistry with Quality Assurance 6 Mandatory
CR_SCHEM_7 Bachelor of Science in Analytical and Pharmaceutical Chemistry 6 Mandatory